Cython

https://cython.org/

http://docs.cython.org/en/latest/src/tutorial/cython_tutorial.html#cython-hello-world

vi setup.py

from distutils.core import setup
from Cython.Build import cythonize

setup(
    ext_modules = cythonize("helloworld.py")
)

$ python setup.py build_ext --inplace